In my quest to streamline my office work, I have found a really nice program that allows you to remap your mouse buttons.It works with any piece-of-crap mouse your company has to offer. Better yet, it is a portable app, meaning you can install it on your company computer without administrator rights.

I currently have the middle and right mouse button changed to "copy" and "paste". I can now do simple Excel filing with one hand 80% of the time. To me it's like a dark age monk discovering printing technology after having hand-written half the Bible.

Link here:
http://highrez.co.uk/downloads/XMouseButtonControl.htm